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Regional banks can appeal to those who are looking for a financial institution with a local feel that still has a wide array of products and services available. While the definition of what constitutes a regional bank may vary, to be eligible in this category, GOBankingRates only considered banks with locations in fewer than 25 states. 

The banks in the Best Midwest Regional Banks category have locations in Iowa, Illinois, Indiana, Kansas, Michigan, Minnesota, Missouri, North Dakota, Nebraska, Ohio, South Dakota and/or Wisconsin.

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Compare the Best Regional Banks in the Midwest

Bank

Best For

Products Offered

Fees

Savings APY

Branch Access

Learn More

Associated Bank, N.A.

4.2
GOBankingRates scores and rankings are objectively determined by our research/editorial team. Our scoring formula weighs several factors that differ from category to category depending on what consumers want from varying products and banks. Read our full Editorial Guidelines here.

Best for Range of Products

Checking, savings, CDs, money market, etc.

$0-$25 monthly, can be waived

IL, MN and WI

Fifth Third Bank, N.A.

4.6
GOBankingRates scores and rankings are objectively determined by our research/editorial team. Our scoring formula weighs several factors that differ from category to category depending on what consumers want from varying products and banks. Read our full Editorial Guidelines here.

Best for Specialized Accounts

Checking, savings, CDs, money market, etc.

$0-$5 monthly, can be waived

1,000+ branches across OH, FL, GA, IL, IN, KY, MI, NC, SC, TN and WV

The Huntington National Bank

4.4
GOBankingRates scores and rankings are objectively determined by our research/editorial team. Our scoring formula weighs several factors that differ from category to category depending on what consumers want from varying products and banks. Read our full Editorial Guidelines here.

Best for Banking Perks

Checking, savings, CDs, money market, etc.

$0-$25 monthly, can be waived

1,000+ branches across CO, FL, IL, IN, KY, MI, MN, OH, PA, WV and WI

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GOBankingRates Best Regional Banks in the Midwest

Best for range of products

Associated Bank, N.A.

4.2
ReviewGOBankingRates scores and rankings are objectively determined by our research/editorial team. Our scoring formula weighs several factors that differ from category to category depending on what consumers want from varying products and banks. Read our full Editorial Guidelines here.

Products Offered

Checking, savings, CDs, money market, etc.

Savings Account APY

Branch Access

IL, MN and WI

WHY WE LIKE ASSOCIATED BANK

Associated Bank brings the Midwest great checking options, which you can link to your money market, CD or savings accounts to earn higher interest rates. We like that it gives you a variety of financial options and products for your personal, business or commercial needs. 

If you live in Illinois, Minnesota or Wisconsin, Associated Bank may be just the right fit for you financially. Be sure to note the ways you can waive the monthly service fees or get overdraft protection to make the most out of your checking and savings. The bank also gives customers access to a network of over 30,000 fee-free ATMs and has debit and credit card perks for sports fans.

PROS & CONS

Pros

  • Multiple options for personal, business and commercial accounts
  • Surcharge-free access to more than 30,000 ATMs
  • Fan debit and credit cards give sports fans extra perks

Cons

  • Low APYs
  • High fees

WHO IT’S BEST FOR

Associated Bank is best for customers within its three-state service area who prefer to do all their banking in one place. It’s also better for customers who feel confident they can keep a decent sum of money in their accounts or receive regular direct deposits, as these actions can get the monthly service fees waived.

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Best for Specialized Acounts

Fifth Third Bank, N.A.

4.6
ReviewGOBankingRates scores and rankings are objectively determined by our research/editorial team. Our scoring formula weighs several factors that differ from category to category depending on what consumers want from varying products and banks. Read our full Editorial Guidelines here.

Products Offered

Checking, savings, CDs, money market, etc.

Savings Account APY

Branch Access

Over 1,000 branches across OH, FL, GA, IL, IN, KY, MI, NC, SC, TN and WV

WHY WE LIKE FIFTH THIRD BANK

If you live in the Midwest and are looking for a single institution that can cover all your banking needs, you should think about Fifth Third Bank.

We consider Fifth Third Bank one of the best in the region thanks to its wide array of banking products, including checking accounts, savings accounts, college funds, retirement accounts and investment accounts. While it offers a range of specialized checking and savings accounts, the account that truly stands out is the Preferred Checking account, a winner in the Best Premium Checking Accounts category.

PROS & CONS

Pros

  • Wide variety of products, including investments and insurance
  • Better interest rates when you have multiple accounts
  • Specialized checking accounts

Cons

  • Limited service area
  • Low rates except on promotional CDs

WHO IT’S BEST FOR

Fifth Third Bank is best for those who like a specialized banking experience and want to have multiple accounts within one bank. Its large number of branches means that anyone in its service area can easily bank in person or online.

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Best for Banking Perks

The Huntington National Bank

4.4
ReviewGOBankingRates scores and rankings are objectively determined by our research/editorial team. Our scoring formula weighs several factors that differ from category to category depending on what consumers want from varying products and banks. Read our full Editorial Guidelines here.

Products Offered

Checking, savings, CDs, money market, etc.

Savings Account APY

Branch Access

Over 1,000 branches across CO, FL, IL, IN, KY, MI, MN, OH, PA, WV and WI

WHY WE LIKE THE HUNTINGTON NATIONAL BANK

Location matters when you want a comprehensive full-service bank experience, and Huntington Bank has a strong presence in the Midwest with over 1,000 branches and more than 1,600 ATMs in the U.S.

What sets Huntington Bank apart is its broad range of banking products (including interest checking), along with perks you don’t often find at regional banks, like overdraft fee relief, no-interest lines of credit and all-day deposits.

PROS & CONS

Pros

  • Overdraft fee relief
  • $100-$500 line of credit that can be repaid with no interest or fees over 3 months
  • Account tiers that come with extra benefits like interest checking and credit monitoring

Cons

  • Varying minimum balances for different accounts
  • Low APYs
  • Limited service area

WHO IT’S BEST FOR

The Huntington National Bank is best for customers within its 11-state service area who like to have a lot of account options with their banking institution, including an interest-bearing checking account.

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Research Methodology

To discover the Best Regional Banks, GOBankingRates looked at the top regional institutions (excluding online banks, and neobanks) located in under 25 states. To determine rankings, GOBankingRates looked at the following factors: (1) total assets as sourced from the FDIC; (2) checking product minimum deposit; (3) monthly checking fee ratio (percent the minimum to avoid fee compared to the monthly fee itself); (4) savings product minimum deposit; (5) savings product APY; (6) Bauer rating (out of 5 stars); (7) products/services offered (auto loans, mortgage loans, credit cards, investment services and insurance); and (8) the average mobile app rating between the Google Play (Android) and Apple stores. All factors were then scored and combined, with the lowest score being the best. Factors (1), (2) and (4) weighed 0.5 times, factor (5) weighed 2.5 times; and factor (7) weighed 1.5 times. All data is up to date as of Nov. 8, 2023; rates and fees are subject to change.

For regional breakdowns, the same methodology as above is used. The following is how we broke down the regions: West (AK, CA, CO, HI, ID, MT, NV, OR, UT, WA, WY); Southwest (AZ, NM, OK, TX); Midwest (IA, IL, IN, KS, MI, MN, MO, ND, NE, OH, SD, WI); Southeast (AL, AR, DC, FL, GA, LA, KY, MS, NC, SC, TN, VA, WV); and Northeast (CT, DE, MA, MD, ME, NH, NJ, NY, PA, RI, VT). To be considered for a region, a bank had to have a branch in one of the states listed and be headquartered in that state/region.

What To Know About Regional Banks

As the name suggests, regional banks are concentrated primarily in one U.S. region. This distinguishes them from national banks, which have a presence throughout the country. While smaller than national banks, regional banks are typically larger than community banks and may offer more products and services, as well.

Who Should Use a Regional Bank

If you would like to bank with an institution with strong ties to your local community, a regional bank may be a good option. Regional banks typically have numerous ATM and bank branches within a given area and also may offer high interest rates and low fees, particularly when compared to national banks.

Pros and Cons of Regional Banks

Regional banks come with their own unique set of advantages and disadvantages.

Pros 

  • Many account options are typically available
  • Numerous ATM and branch locations throughout a given region
  • Contributes to the local community
  • Lower account fees and higher APYs than national banks

Cons

  • Not convenient if you frequently travel outside your region
  • Smaller range of products and services compared to national banks

How Regional Banks Compare to Other Banks

There are many types of banks available. Here’s what to know about how regional banks stack up to other types of financial institutions.

Regional Banks vs. National Banks

The biggest difference between regional banks and national banks is the number of locations. National banks will have locations throughout the U.S., while regional banks have locations concentrated in a specific region. Because national banks are larger in scope, they often offer a wider range of products and services and have more assets behind them.

Regional Banks vs. Retail Banks

Retail banks serve the general public. Many regional banks are retail banks, so the differences between these two bank types will depend on the specific banks you are considering.

Regional Banks vs. Investment Banks

Regional banks serve everyday banking clients, while investment banks serve corporate clients and institutions.

Regional Banks vs. Credit Unions

Credit unions are nonprofit entities that are owned by their members. While regional banks may offer similar products and services as credit unions, the overall business model is different. Credit unions are also often smaller than regional banks.

How To Choose a Regional Bank

When selecting a regional bank, pay attention to the following factors:

  • Location: Does the bank have ATMs and branch locations near you?
  • Availability: Do the bank’s hours of operation match your needs? What holidays are they closed for?
  • Bank health: Is the bank raising enough assets and generating enough profit to remain solvent?
  • Rewards and promotions: How do sign-up bonuses, reward programs and other promotions compare to what’s available at other institutions?
  • Account offerings: What bank accounts does the bank offer? Does it serve all of your banking needs?

Heather Taylor contributed to the reporting for this article.

Recap of Winners

  • Associated Bank, N.A. – Best for Range of Products
  • Fifth Third Bank, N.A. – Best for Specialized Accounts
  • The Huntington National Bank – Best for Banking Perks

See Best Banks Winners From All Categories

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